Grade 12 Science Courses: Biology vs Chemistry vs Physics

grade 12 biology vs chemistry vs physics

Choosing the right grade 12 biology vs chemistry vs physics course is pivotal for Ontario high school students. Whether you’re aiming for a health sciences program, an engineering degree, or just fulfilling Ontario high school science credits, the course (or courses) you pick can shape your post-secondary path. In Ontario, the main Grade 12 Science Courses at the university-preparation level are Biology (SBI4U), Chemistry (SCH4U), and Physics (SPH4U). Each has unique content, challenges, and benefits. This comprehensive guide will compare SBI4U vs SCH4U vs SPH4U, helping you understand their differences and decide which course aligns best with your interests and goals.

Ontario students must earn at least two science credits (typically in Grades 9 and 10) to meet OSSD requirements. Grade 12 sciences are optional credits, but they become essential if you’re pursuing science-related fields. We’ll break down each Grade 12 science, compare their content and difficulty, and discuss which courses are most relevant for programs like health sciences, engineering, or general science degrees. We’ll also provide a handy comparison chart and answer frequently asked questions. By the end, you’ll be equipped to choose the right course—and even consider taking your OSSD online courses through an accredited school like Canadian Virtual School for flexibility. Let’s dive into the world of Grade 12 science!

Understanding grade 12 biology vs chemistry vs physics

In Ontario, Grade 12 science courses are categorized as “4U” (Grade 12 University preparation) and have specific course codes: SBI4U (Biology), SCH4U (Chemistry), and SPH4U (Physics). These courses are designed to prepare students for university programs in science and related fields. Each course builds on the Grade 11 U-level science (the prerequisite for the Grade 12 course), delving deeper into subject-specific concepts. For example, to take Grade 12 Biology (SBI4U), you must complete Grade 11 Biology (SBI3U); SCH4U requires Grade 11 Chemistry and SPH4U requires Grade 11 Physics.

All three courses emphasize advanced scientific skills like inquiry, analysis, and problem-solving. However, their content and approach differ:

  • Biology (SBI4U) explores living systems and is heavy on theory and memorization of processes.
  • Chemistry (SCH4U) focuses on chemical reactions and problem-solving using theory and math.
  • Physics (SPH4U) centers on physical laws and mathematical analysis of motion, energy, and forces.

Each Grade 12 science course counts as a full credit toward the Ontario Secondary School Diploma and can fulfill the “additional science credit” requirement for graduation if needed. Importantly, these courses often serve as prerequisites for university admissions in science-related programs. Below, we’ll look at each course in detail, then compare them.

Grade 12 Biology (SBI4U)

Grade 12 Biology (SBI4U) is all about the science of life. In SBI4U, students examine biological processes at the molecular, cellular, and systemic levels. Major units include biochemistry, metabolic processes (how organisms obtain and use energy), molecular genetics (DNA, gene expression), homeostasis (maintaining internal equilibrium in organisms), and population dynamics. In other words, you’ll study everything from the chemicals that make up living cells to the way whole ecosystems function.

SBI4U is a content-rich course that emphasizes understanding concepts and memorizing details. You will conduct experiments and investigations to see biology in action, often involving microscopy, biochemical tests, or simulations. Through these activities, you’ll hone skills in scientific research, data analysis, and report writing. There is a strong focus on scientific literacy and communicating biological information effectively, which means you’ll practice reading research, analyzing graphs, and discussing biology’s ethical and technological implications in society.

Difficulty: Many students find biology approachable because it’s less math-intensive than physics or chemistry. However, the challenge in SBI4U lies in the breadth and depth of content. There’s a lot of terminology and complex processes (think cellular respiration, photosynthesis, DNA replication) to learn. Success in Biology often requires good memory, attention to detail, and strong reading comprehension. You might find Biology enjoyable if you enjoy learning about living things and don’t mind studying diagrams or detailed processes. If memorization is not your strength, be prepared to spend extra time reviewing notes and making study aids (like flashcards or concept maps). On the bright side, concepts in biology are very tangible, relating to your own body or the environment, making them easier to grasp and interesting to explore.

Relevance and Ideal For: SBI4U is an excellent choice if you’re interested in health sciences, medicine, or life science programs. It provides a foundation for biology, biochemistry, health/medical sciences, biotechnology, environmental science, and more university courses. Many post-secondary programs in the health field either require or strongly recommend Grade 12 Biology. For instance, students aiming for medicine, dentistry, nursing, pharmacology, or biology majors will benefit greatly from SBI4U. Some universities specifically recommend taking Biology and Chemistry for biomedical science programs. The lab skills and scientific inquiry practice you gain in SBI4U also help you prepare for any science-related degree.

Key skills developed: By taking SBI4U, you’ll strengthen skills in research and laboratory techniques, critical thinking (especially analyzing experimental results), and written communication through lab reports and projects. You’ll also gain a deeper understanding of human biology and ecology, which you can carry into everyday life and informed decision-making (like understanding health news or environmental issues).

Prerequisite: Grade 11 Biology, University level (SBI3U) is required before taking SBI4U. If you haven’t taken Grade 11 Biology, you must complete that first (or obtain a prerequisite waiver in exceptional cases). Having that background is essential, as SBI4U builds directly on concepts like cell structure, DNA, and basic physiology introduced in SBI3U.

Grade 12 Chemistry (SCH4U)

Grade 12 Chemistry (SCH4U) delves into the properties and reactions of matter. In SCH4U, you will deepen your understanding of chemical principles through topics such as organic chemistry (the study of carbon-based compounds), structure and properties of matter (atomic and molecular structure, periodic trends), energy changes and rates of reaction (thermochemistry and kinetics), chemical equilibrium (including acid-base and solubility equilibria), and electrochemistry. This array of topics means you’ll explore everything from how batteries produce electricity to why and how reactions speed up or slow down.

Chemistry in Grade 12 is both theoretical and quantitative. Expect to perform experiments (either hands-on in a lab or virtually if online) that might include titrations, qualitative analysis of ions, organic synthesis, or electrochemical cells. Through these labs, you’ll practice precise measurement, observation, and lab safety. Problem-solving is a massive component of SCH4U – you’ll tackle calculations involving reaction stoichiometry, energy changes, equilibrium constants, pH, and more. The course emphasizes refining your ability to communicate scientific data and systematically analyze chemical problems. You’ll also discuss real-world applications of chemistry, such as the role of chemistry in environmental issues and technology (for example, understanding chemical pollutants or the chemistry behind pharmaceuticals).

Difficulty: Many consider chemistry the “middle ground” between biology and physics in terms of difficulty. It requires comfort with some math (algebraic manipulation and using formulas), but to a lesser extent than Physics. The challenge in SCH4U often comes from conceptualizing the invisible world of atoms and molecules and mastering the problem-solving techniques for chemical calculations. Topics like equilibrium and organic reaction mechanisms can be abstract. If you have a strong foundation in Grade 11 Chemistry (SCH3U) and decent math skills, SCH4U is manageable – even fun, as you puzzle out how to make reactions yield the desired products. Students who enjoy logical problem-solving and practical experiments tend to do well. If you struggled in Grade 11 Chemistry or dislike math, be prepared to seek extra help and practice regularly. The good news is that chemistry concepts are highly interconnected; once you grasp the core principles, you can often apply them to many different problems (for example, the idea of equilibrium appears in acids/bases, solubility, etc.).

Relevance and Ideal For: SCH4U is essential for many pathways, especially in engineering, chemical, and medical sciences. In Ontario, engineering programs require Grade 12 Chemistry (along with Physics) for admission. It’s also usually required for programs like pharmacy, biochemistry, environmental science, food science, and various tech or science degrees. Even for life science or health programs, Chemistry is often required or highly recommended because biochemical processes underlie much of biology. For example, understanding organic chemistry and biochemistry is crucial to enter medicine or pharmacology. SCH4U also develops your quantitative analytical skills, which are valued in fields like forensic science, geology, and engineering technology. If you’re considering a career in chemistry, chemical engineering, pharmacy, environmental science, or forensics, taking SCH4U is the right choice.

Key skills developed: Grade 12 Chemistry will enhance your analytical and problem-solving skills. You’ll learn to approach complex problems step-by-step (a skill useful far beyond chemistry). Laboratory work in SCH4U teaches careful experimental design, observation, and data analysis. You’ll also practice communicating scientific findings clearly, often through lab reports or presentations. Importantly, Chemistry teaches you to connect microscopic concepts (atoms and molecules) to macroscopic observations (what we see and measure). This ability to link theory with reality is a valuable skill in any scientific or engineering field.

Prerequisite: Grade 11 Chemistry, University level (SCH3U) is required before taking SCH4U. The Grade 11 course covers fundamental concepts (like the mole, basic reactions, atomic structure and bonding) that Grade 12 builds upon. Please ensure you’re comfortable with those Grade 11 topics, as SCH4U will expand on them quickly. If it’s been a while since you took Grade 11 Chem, consider reviewing your notes or doing a refresher before the Grade 12 course begins (some courses even start with a brief review unit).

Grade 12 Physics (SPH4U)

Grade 12 Physics (SPH4U) studies the fundamental laws governing energy and matter. In SPH4U, students deepen their understanding of physics concepts and theories introduced in Grade 11. Key units typically include kinematics and dynamics (advanced study of motion and forces, extending into circular motion and more complex systems), energy and momentum (including work, power, momentum conservation, and energy transformations), gravitational, electric, and magnetic fields (understanding forces at a distance and field theory), waves and sound (wave nature of light), and modern physics (often covering basics of quantum mechanics and Einstein’s theory of relativity). Essentially, SPH4U spans topics from Newtonian mechanics to electromagnetism to the frontiers of 20th-century physics.

Physics is a highly analytical course. Expect to solve many problems using formulas and algebra – everything from calculating the trajectory of a projectile to determining the electric field around a charged object. Labs and activities in SPH4U might include experiments like measuring acceleration due to gravity, mapping electric fields, exploring circuits, and analyzing motion through video. Even if you’re taking the course online, virtual lab simulations allow you to perform experiments (such as adjusting variables in a pendulum or circuit simulation and collecting data). Through these investigations, you’ll learn how to analyze data qualitatively and quantitatively, using graphs and calculations to conclude. Physics also emphasizes modelling real-world phenomena: you’ll learn how simplifying assumptions and theoretical models help predict actual behaviour, and where the limits of those models are.

Difficulty: Physics 4U is often regarded as one of Ontario’s most challenging high school courses. The reason is twofold: the concepts can be abstract (especially topics like electric fields or quantum theory), and the course demands strong mathematical skills. You’ll need a good grasp of algebra, and while calculus is not required, some problems involve understanding the concept of rates of change conceptually. If math is a strong subject for you and you enjoy logical puzzles, physics may be rewarding and fun. Many students find satisfaction in how physics problems have a clear solution when approached methodically. However, if you’re weaker in math or found Grade 11 Physics difficult, expect to put in extra effort. Regular practice is key – solving many problems is the only way to get comfortable with the formulas and problem types. Don’t be afraid to ask your teacher for help or use extra resources; sometimes a different explanation can make a tricky concept click. One encouraging point is that because SPH4U covers various topics, students often enjoy at least some sections (for example, you might struggle with fields but love the relativity or vice versa). Physics can be rigid, but it’s also incredibly eye-opening – it lets you understand how the world (and universe) works at a fundamental level.

Relevance and Ideal For: SPH4U is necessary for any student contemplating an engineering or physical sciences pathway. All Ontario university engineering programs require Grade 12 Physics (SPH4U) for admission (along with Chemistry). Physics is also required or highly recommended for physics, astronomy, computer science, and mathematics degrees. Even life science students can benefit from physics – for example, kinesiology or biomechanics programs look favourably on students with physics, and some health science programs require a physics credit. If you’re interested in fields like mechanical or electrical engineering, aerospace, architecture (for structural principles), or computer engineering, SPH4U will provide essential background knowledge. Moreover, the problem-solving mentality developed in physics is excellent preparation for computer science and data science. In short, taking Physics will serve you well if your future studies involve technology, machines, or the fundamentals of matter and energy.

Key skills developed: Physics teaches you to break down complex problems into manageable parts – an extremely valuable skill in any discipline. You’ll improve your mathematical reasoning, learn to apply formulas to real situations, and strengthen your understanding of designing experiments to test hypotheses. Physics also fosters critical thinking: often deciding which principles or formulas apply in a scenario is a higher-order thinking skill. Additionally, you’ll become comfortable using technology (like simulations or graphing tools) to analyze physical phenomena. Finally, SPH4U gives you practice in communicating solutions clearly, often by showing step-by-step calculations and explaining reasoning, similar to how it’s done in university exams and assignments.

Prerequisite: Grade 11 Physics, University level (SPH3U) is required before taking SPH4U. The Grade 11 course is crucial for introducing basic kinematics, forces, energy, waves, and simple electricity. If you did well in SPH3U, you have a solid foundation. If you haven’t taken Grade 11 Physics and attempted SPH4U, you’ll find yourself at a significant disadvantage, as SPH4U assumes familiarity with those fundamental concepts. Ensure you’ve mastered things like Newton’s laws, fundamental circuit laws (Ohm’s law), and simpler wave concepts from Grade 11, as Grade 12 will extend those into more complex territory.

SBI4U vs SCH4U vs SPH4U: Key Differences

Now that we’ve outlined each Grade 12 science course, let’s compare Biology, Chemistry, and Physics directly. Each course has its own focus, skill set, and relevance for future studies. The chart below highlights the key differences in course content, the nature of the challenge (difficulty), and how each aligns with post-secondary paths.

CourseMain Content & FocusSkills Emphasized / Course StyleIdeal For / Post-Secondary Pathways
Biology (SBI4U)Living systems and life processes: biochemistry, metabolism, genetics, homeostasis, population dynamics.
Strong theoretical component with extensive factual content.
Health Sciences & Life Sciences: Ideal for students aiming for medicine, nursing, pharmacy, biotechnology, environmental science, or biology-related fields.
It provides a foundation for university biology programs and develops an understanding of living systems (which is valuable for any medical/health career).
Chemical reactions and properties of matter: organic chemistry, structure of matter, thermodynamics and kinetics (energy changes, reaction rates), equilibrium (acid-base, etc.), and electrochemistry.
Chemistry (SCH4U)Analytical Problem-Solving: Requires algebraic calculations (stoichiometry, equilibrium constants, ph, etc.) and logical reasoning.
Laboratory Technique: Emphasis on precise measurement (titrations, syntheses), observation, and safety in experiments.
Application of Concepts: Connects theory to real-world chemical applications (e.g., environmental chemistry, industrial processes).
Mathematical Reasoning: Heavy use of formulas and algebra to solve problems; abstract thinking to understand concepts like fields and modern physics.
Experimental Analysis: Use of experiments/simulations to investigate principles (e.g., motion, circuits) and analyze data quantitatively.
Critical Thinking: Modelling real-world scenarios, making assumptions for problem-solving, and understanding technological applications of physics.
Physical Sciences, Engineering, Chemistry-related fields: Essential for engineering (chemical, mechanical, etc.) – most engineering programs require SCH4U.
Required or recommended for chemistry, biochemistry, pharmacology, environmental science, forensic science, and health science programs.
Builds strong quantitative and lab skills that are valuable in any science/tech career.
Physics (SPH4U)Fundamental laws of nature: advanced dynamics (forces and motion), energy and momentum, fields (gravitational, electric, magnetic), electromagnetic radiation, and introductions to quantum mechanics and relativity.Engineering, Technology, Physical Sciences: SPH4U is crucial for all engineering disciplines (civil, mechanical, electrical, etc.). Universities require it for engineering admissions.
Important for degrees in physics, astronomy, computer science, mathematics, and architecture (for structural physics).
Develops problem-solving skills that are beneficial even in non-physics careers (e.g., analytics, programming) due to rigorous logical training.
Mathematical Reasoning: Heavy use of formulas and algebra to solve problems; abstract thinking to understand concepts like fields and modern physics.
Experimental Analysis: Use of experiments/simulations to investigate principles (e.g., motion, circuits) and analyze data quantitatively.
Critical Thinking: Modeling real-world scenarios, making assumptions for problem-solving, and understanding technological applications of physics.

Difficulty Comparison: In general, Physics is often considered the most challenging due to its mathematical nature and abstract concepts, Biology can be difficult due to the volume of information and new vocabulary (though it’s more about remembering and understanding concepts than math), and Chemistry sits in between – it requires both conceptual understanding and problem-solving, but on a manageable scale if you have a solid foundation. Your strengths matter: students strong in math might find Physics more straightforward and Biology more demanding, whereas those who excel in reading/memorization might breeze through Biology but struggle in Physics. Chemistry requires a balance of both kinds of skills. Each course can be mastered with the right study strategies: e.g., Biology with regular review and concept mapping, Chemistry with lots of practice problems and labs, and Physics with step-by-step problem solving and seeking help on challenging concepts.

Workload: All three courses are 1.0 credit courses with around 110 hours of instruction each, and each will involve homework, labs, and tests. Biology might involve reading and note-taking; Chemistry and Physics will involve more practice exercises. Time management and consistent study are key, especially if you plan to take more than one science in the same semester.

Choosing the Right Grade 12 Science Course for Your Goals

How do you decide which Grade 12 science course(s) to take? The answer depends mainly on your interests and your post-secondary goals. Here are some considerations and familiar scenarios to help you choose:

  • If you’re aiming for Health Sciences, Medicine, or Life Sciences:
    Focus on Biology and Chemistry. These two are most relevant for life science programs. Biology (SBI4U) is often recommended or required for health-related university programs like medicine, nursing, biomedical science, or psychology (life science streams). Chemistry (SCH4U) is typically needed for programs like nursing, pharmacy, dentistry, medicine, and biology/biochem majors. Universities often require at least two sciences for admission to life science programs, and having both Bio and Chem covers that. Even if a program doesn’t explicitly require Biology, not having it could put you at a disadvantage in first-year courses (e.g., pre-med students will encounter biology in university), physics is less critical for life sciences. Still, there are exceptions – for example, kinesiology or specific biology programs may want physics, and some competitive health programs like physiotherapy or radiology tech appreciate a physics background. If you are interested in health sciences, consider taking all three sciences to keep every door open (more on managing all three below). But if you prefer to focus, Biology and Chemistry will usually serve you best for a medical/health path. These courses will also develop your understanding of scientific research, an essential skill in medicine and related fields. Plus, taking Bio and Chem in Grade 12 will confirm if you genuinely enjoy those subjects before you commit to a health science program.
  • If you’re aiming for the Engineering or Technology fields:
    Physics and Chemistry are must-haves. All engineering programs in Ontario require Physics (SPH4U) and Chemistry (SCH4U) at Grade 12. Physics is critical because engineering disciplines (like mechanical, electrical, civil, aerospace, etc.) rely heavily on physics principles. Chemistry is required too, as it provides fundamental knowledge of materials and chemical processes (important in fields like chemical, environmental, or materials engineering, and even for understanding basics like why materials fail or how batteries work in electrical engineering). Mathematics is equally essential here (you’ll need Advanced Functions and Calculus & Vectors), but that’s outside the scope of this post – remember to plan your math courses alongside your sciences. What about Biology? Generally, Biology is not required for engineering programs. However, there are a few engineering fields (like biomedical engineering or environmental engineering) where knowledge of biology could be helpful. Still, even in those cases, universities do not usually require SBI4U for admission. If you have room and interest, taking Biology won’t hurt, but prioritize Physics and Chemistry first. They will meet admission requirements and prepare you for the problem-solving nature of engineering coursework. Engineering-bound students often also enjoy the logical structure of physics and the hands-on problem solving of chemistry, which is good practice for engineering design challenges.
  • If you’re interested in Computer Science or Math:
    Surprisingly, none of the Grade 12 sciences is strictly required for most computer science programs – they focus on math (and sometimes require physics or recommend it, but not always). However, having Physics can be beneficial. Fields like computer engineering or any hardware-related computing require physics. Even for software-focused students, physics sharpens your logical thinking and problem decomposition skills, similar to programming thinking. Chemistry and Biology are less directly applicable to comp sci, but if you have an interest in areas like bioinformatics or computational chemistry/physics, then taking the relevant science (Bio for bioinformatics, Chem for computational chemistry, etc.) would give you domain knowledge that could pair with your coding skills later. If you’re science-curious but mainly headed for a CS or math degree, Physics (SPH4U) might give you the biggest payoff in skill development. In contrast, Biology or Chemistry might be for personal interest or to keep a backup plan (e.g., a science dual major) open.
  • If you’re aiming for a General Science degree (B.Sc.):
    Many general science or unspecified science programs (like a general Science entry program) require two of the three 4U sciences. You might take two or even all three sciences in Grade 12 to keep your options open. If you have a leaning, take the two that align with your interests (e.g., if you think you might major in biology or a health field, pick Bio and Chem; if you might go into physics or chemistry, pick Chem and Phys). If you have no idea which science you’ll like most in university, consider taking all three – this way, you’ll fulfill prerequisites for virtually any science program. Just be ready for a heavy workload. Some universities note that while only two sciences are required, taking all three is recommended to be best prepared. Also, if you’re considering architecture or certain environmental science programs, check their specific requirements: occasionally, physics or chemistry is required or recommended. In summary, for a general science pathway, ensure you have at least two sciences, and choose based on what you enjoyed in Grade 11 or what career ideas you have in mind.
  • If you’re considering Business, Arts, or other non-science programs but need a science credit:
    Some students who plan to go into non-science fields still take a Grade 12 science either out of interest or to have a competitive edge in university applications (since universities like to see a well-rounded course load). If you only want to take one science in Grade 12 because you need one more 4u course or you’re just curious, pick the science you are strongest in or most interested in. For many, this is Biology, since it’s perceived as less math-heavy and more directly relatable. Biology can be a good choice if you enjoy learning about living things and want a heavily knowledge-based course. If you prefer logical puzzles and are good at math, you might find Physics or Chemistry more “fun,” even if you’re not pursuing them further. Remember that a Grade 12 science is not required to graduate (only Grade 9/10 science is needed), so this is purely an elective choice. Choosing one can bolster your problem-solving skills (functional even in business or social sciences) and show academic breadth. Just be sure you meet the prerequisite (Grade 11 course) and are ready to commit time to it, as these courses are rigorous. Another tip: check if the university programs you’re eyeing have any science prerequisites – most business or humanities programs don’t, but a few interdisciplinary programs might expect one science. If nothing is required, you truly have the freedom to pick based on interest.
  • If you want to “keep options open”:
    Many students are unsure about their exact path, so they depend on science to keep doors open. This is a valid strategy, as long as you can handle the workload. Taking all three (Biology, Chemistry, Physics) in Grade 12 provides maximal flexibility – you could go into any science, engineering, or even change your mind and go into something else (you’d still have these as strong credits on your transcript). Universities look at your top 6 4U/M marks, so if you take three sciences, all three could count toward that top 6 if you do well. Balancing three heavy courses (often alongside Advanced Functions and Calculus for those same students!) is challenging. One way to manage this is by taking one or more of them through an online school like Canadian Virtual School, either during summer or spread out, so you’re not handling all three simultaneously in a single semester. Online courses allow you to learn at your own pace and time, which can reduce stress if your day school schedule is packed. Many students take, for example, Physics online if they find it intimidating, to give themselves more time to absorb the material. As long as the online course is from an accredited institution, it will count the same as a regular school credit, and universities will accept it. So, if you genuinely want to keep all options open, it is feasible to do all three sciences – plan carefully and use summer or online options to distribute the effort.
  • Considering Your Enjoyment and Strengths:
    It’s not all about external requirements – your interest matters too. You will perform better in a course you find engaging. Think back to Grade 11 (or Grade 10) science: which units or projects did you enjoy the most? If dissections and ecology were thrilling, but balancing chemical equations was torture, that’s a vote for Biology. If you loved the chemistry lab where you made different salts or the physics project on building a catapult, factor that in. Sometimes students automatically choose courses based on what they think they “should” take for a career, but interest often translates to better grades, affecting admissions. There is usually some wiggle room in program requirements, especially for programs that only say “one of or two of” the sciences. For example, if a program requires two sciences and you love biology and physics but not chemistry, you can do those two, check specific prerequisite combinations. Play to your strengths: universities generally don’t require all three, so you can drop the one you dislike the most (unless your chosen field demands it). Remember, a high mark in a slightly less related course might be better for admissions than a low mark in a “required” course for some fields. That said, never drop a required course for your dream program – but if it’s not explicitly required, you have some flexibility.
  • Think about Skills, Not Just Content:
    Each science will also help you build specific skills. Biology will enhance your ability to memorize, synthesize information and write scientific explanations. Chemistry will sharpen your quantitative problem-solving and laboratory technique. Physics will improve your mathematical modelling and critical thinking. Consider which skill set you want to develop more. For instance, if you’re heading into a field like economics or psychology – neither explicitly needs Grade 12 science – you might still take Physics or Chemistry to bolster analytical skills, or Biology to get comfortable with research and data (proper in psychology). In other words, the benefit of these courses can also be general: they make you a more well-rounded, scientifically literate graduate, which is valuable in today’s world. Many employers and post-secondary programs appreciate the discipline and analytical training that comes with completing advanced science courses, even if it’s not directly in that field.

The bottom line is to align your Grade 12 science choices with your passion and plans. If you have a clear career goal (doctor, engineer, etc.), use that as a guiding star for what’s required. If you’re undecided, consider taking at least two sciences to keep pathways open, selecting the ones you are strongest in or most curious about. And remember – it’s not uncommon for students to take all three, or to take one at day school and another online, etc. Canadian Virtual School (CVS) offers all these Grade 12 science courses online, giving you flexible options to get the necessary credits without overwhelming yourself. However you choose to do it, challenge yourself, and set yourself up for success by playing to your strengths.

Quick Tips for Success in Any Grade 12 Science Course:

  • Stay organized and don’t fall behind. The content builds up quickly. Regular review can save you from last-minute cramming.
  • Do lots of practice. Practice problems are key for Chemistry and Physics. Answering questions in detail and quizzing yourself on terms helps retention in biology.
  • Engage with labs and projects. These make concepts concrete. Even in an online course, take simulations seriously – they solidify your understanding, and labs/projects are often heavily weighted in grading.
  • Ask for help when needed. Whether from your teacher, a tutor, or peers, don’t hesitate if you’re confused. Clearing up one concept can unlock understanding for an entire unit.
  • Use resources. Textbooks, online videos, study guides, and class notes are all valuable. For example, many students use YouTube tutorials for tough physics problems or online animations for biology processes.
  • Keep the end goal in mind. Knowing why you’re taking the course (e.g., “I need this for engineering” or “I genuinely want to learn about human anatomy”) will motivate you during tough times.

Now, let’s address some frequently asked questions students often have about Grade 12 science courses in Ontario:

Frequently Asked Questions (FAQs)

Are Grade 12 science courses mandatory to get an OSSD?

No, Grade 12 science courses are not mandatory for the Ontario Secondary School Diploma. The OSSD requires two science credits, which students typically earn in Grade 9 and 10. Grade 11 and 12 sciences are optional courses that you choose based on your interests and post-secondary plans. However, while they aren’t required to graduate high school, Grade 12 Science Courses like SBI4U, SCH4U, and SPH4U often become de facto requirements for science, engineering, or health university programs. In short, you can graduate without taking Grade 12 Biology, Chemistry, or Physics, but if your future program needs them, they effectively become “required” for you.

What’s the difference between SBI4U, SCH4U, and SPH4U?

SBI4U is Grade 12 Biology, focusing on life sciences (e.g. biochemistry, genetics, human systems, ecology). SCH4U is Grade 12 Chemistry centred on chemical principles (like reactions, equilibrium, and organic chemistry). SPH4U is Grade 12 Physics, dealing with physical laws of the universe (motion, forces, energy, waves, etc.). Each course has a distinct emphasis: Biology is heavy on concepts and memorization of processes, Chemistry combines conceptual understanding with mathematical problem-solving in a lab context, and Physics is very math-driven with theoretical and practical problem-solving. They also differ in relevance: SBI4U is aligned with health/life science pathways, SCH4U with chemistry/engineering pathways, and SPH4U with engineering/physical science pathways. (See the comparison chart above for a detailed breakdown of content and skills for each course.)

Which Grade 12 science course is the hardest?

The hardest” can vary according to student strength, but many find Grade 12 Physics (SPH4U) the most challenging because it involves advanced math and abstract concepts like electricity and magnetism, quantum theory, etc. Physics problems often require multi-step algebra and a firm grasp of theoretical principles, which can be tough if math isn’t your forte. Chemistry (SCH4U) is also challenging but tends to be easier for those with solid math and logic skills; its difficulty lies in mastering concepts like equilibrium and organic reactions and doing calculations (e.g. in stoichiometry or pH). Biology (SBI4U) is often considered the least technically difficult since it involves less math; however, it can be challenging regarding content volume. There’s a lot of memorization (think of complex processes like protein synthesis or feedback systems in physiology) and understanding of detailed concepts.In summary, Physics is tough for many due to math and abstraction, Chemistry is moderately strenuous due to conceptual + mathematical balance, and Biology is tough if you struggle with memorization or synthesizing lots of information. Your strengths will determine which one feels hardest. Students strong in math might say Biology is hardest (because it’s a lot of reading), while those strong in reading/memory might say Physics is hardest. All three are high-level courses, but you can do well in any of them with consistent work

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Which Grade 12 science should I take if I want to go into medicine or health sciences?

If you aim for medicine, dentistry, nursing, pharmacy, or related health science programs, you should take Grade 12 Biology (SBI4U) and Grade 12 Chemistry (SCH4U). These two are most directly relevant to the medical and health fields. Universities often require Chemistry to be admitted to health programs (some require Biology, or will certainly cover its content in the first year). Biology will give you a foundation in topics like human physiology and genetics, which are helpful for health/medical studies. Chemistry is crucial for understanding biochemistry, pharmacology, and the chemical basis of bodily processes – plus it’s a requirement for programs like nursing, pharmacy, etc. Physics (SPH4U) is generally not required for medical or health science undergraduate programs, but having it can be advantageous. For example, some competitive programs (like certain kinesiology or health science programs) recommend physics, and the MCAT (Medical College Admission Test) includes physics concepts. So taking SPH4U could help in the long run. However, if scheduling or bandwidth is a concern, prioritize biology and chemistry first for a path in health sciences. They will cover prerequisites for almost all health-related university programs and give you relevant knowledge for your future studies.

What science courses do I need for engineering programs?

For engineering in Ontario, you must take Grade 12 Chemistry (SCH4U) and Grade 12 Physics (SPH4U). Virtually all engineering undergraduate programs list these two courses as required prerequisites. Engineering programs (mechanical, civil, electrical, chemical, etc.) rely on physics and chemistry fundamentals. Physics is crucial for understanding mechanics, electricity, thermodynamics, and other core topics in engineering. Chemistry is needed especially for chemical, materials, and environmental engineering and generally for understanding material properties and processes. In addition to these sciences, engineering programs require Grade 12 Advanced Functions (MHF4U), Calculus & Vectors (MCV4U), and Grade 12 English. Biology (SBI4U) is not needed for engineering admissions and typically won’t factor into the engineering curriculum, so it’s optional. You could take it if you have room and interest, but it won’t impact your engineering admission. Some specialized programs like biomedical engineering or specific tech fields might find a biology helpful background, but again, not an admission requirement. So, if you’re set on engineering, focus on Physics and Chemistry (and your maths). Ensure you perform well in those, as engineering admissions are competitive and will look closely at those marks. Remember that engineering is heavy in physics-based problem solving, so having a firm grasp of SPH4U content will make your first year in engineering much easier.

Can I take Grade 12 Chemistry without taking Grade 11 Chemistry?

Generally, you cannot take SCH4U without the SCH3U prerequisite (Grade 11 Chemistry). Ontario’s curriculum has prerequisites for a reason: Grade 11 Chemistry covers fundamental concepts (atomic structure, bonding, basic reactions, mole calculations, etc.) that Grade 12 builds on. Schools (including online schools) will typically not allow registration in a 4u science if you haven’t completed the corresponding 3u course (or equivalent). For example, the prerequisite for SCH4U is Chemistry, Grade 11, University Prep. The same goes for Biology and Physics (each 4U needs the 3U). The only exceptions might be if you are a mature student or under special permissions (for instance, some adult students over 19 can request to take a course without the prerequisite, or if you have done similar coursework elsewhere). However, for a current high school student, plan to take the Grade 11 course first. Even if somehow allowed, it’s not advisable – jumping into Grade 12 Chem without a Grade 11 background would be overwhelming and likely result in poor performance. If you missed Grade 11 Chemistry and now need Grade 12, consider taking Grade 11 in summer school or online first. The same logic applies to attempting SPH4U without SPH3U, or SBI4U without SBI3U – it’s not allowed in the standard progression (prerequisites are enforced) and would set you up for struggle. So, ensure you have the Grade 11 science before you tackle the Grade 12 course.

Is it a good idea to take all three Grade 12 science courses?

Taking all three (Biology, Chemistry, and Physics 4u) is a big commitment, but it can be a good idea for some students. If you are pursuing a highly science-intensive path (for example, you’re considering a general science degree, undecided between medicine and engineering, or you want to prepare for a science-heavy university workload), having all three can keep every door open. Universities often require two sciences for science programs, but recommend having all three if possible – for instance, physical science programs might recommend Biology in addition to mandatory Physics and Chemistry, just for breadth. Taking all three’ll also complete the new online learning requirement if some are taken online (more on that next). However, be realistic about your time and abilities. These courses each demand a lot of study and work; taking all three in the same semester is challenging. Many students handle it by taking one or two classes in the summer or online to spread them out. If you have a strong aptitude and passion for science and have done very well in Grade 11 sciences, you’re a good candidate to take all three. If you struggled in one of the Grade 11 sciences, it might be risky to take the 4U level of that subject on top of two others. One strategy is to look at your Grade 11 marks: if you have, say, high 80s or 90s in all three Grade 11 sciences, you likely can manage all three 4Us with proper effort. If one was significantly lower or caused you stress, you might consider leaving that one out in Grade 12 unless you need it. Taking all three can also show universities that you’re a hardworking, well-rounded candidate, but your marks in them matter more, so don’t sacrifice your GPA by overloading. In summary, it’s a good idea only if you have a strong ability in science and need the flexibility; otherwise, it’s perfectly fine to take two (or even just one if that’s all you need for your goal)—quality over quantity.

Will universities accept Grade 12 science credits earned online (at a private online school)?

Yes. University admissions treat an Ontario Grade 12 U-level credit the same way, whether earned in-person at a public school, private school, or online. The key is that the credit must be from an Ontario Ministry of Education–inspected school. For example, Canadian Virtual School (CVS) is an inspected private online high school authorized to grant OSSD credits. Credits from such institutions are recorded on the Ontario Student Transcript and are fully recognized by universities and colleges. All universities and colleges in Ontario will accept credits from any Ministry-inspected online school if the course code is the correct 4U credit. Thousands of students in Ontario take one or more of their Grade 12 courses online every year – universities are very familiar with this and do not penalize applicants for it. The marks you earn online count toward your admissions average just like any other marks. One thing to be mindful of is timing: ensure you complete the online course in time for the marks to be available for university admission deadlines. Also, universities might look at where the course was taken (as a note, not usually for judgment, but just for records). As long as your online school is legitimate (CVS is a leading private online school in Ontario), you can be confident that the credit is as good as any day-school credit. So if you choose to take SCH4U or SPH4U online to manage your schedule or learning pace better, you can do so without worrying about university recognition. It’s always a good idea to inform your Guidance counsellor and ensure the credit is correctly added to your transcript via the Ontario Student Record (OSR) process. But rest assured, an online credit earned from an accredited institution is equivalent to those earned in person.

How do lab experiments work in an online science course?

Online science courses still include lab investigations – they’re just delivered differently. Accredited online schools like CVS incorporate virtual labs, simulations, and at-home experiments to meet the lab component of the curriculum. For example, you might use an interactive simulation to perform a chemistry titration or to measure motion in a physics experiment. These virtual labs allow you to change variables and record data similarly to a hands-on lab. In Biology, you might do a virtual dissection, use an online microscope simulation, or even conduct a simple experiment at home (like an osmosis experiment with household materials) with Guidance from the course. Schools often use specialized software or websites that realistically mimic the experiment (for instance, observing how pH changes in a virtual beaker when you add acid, or measuring the pendulum’s motion on screen). You will typically be required to complete lab worksheets or write lab reports based on these activities, just as in a regular class. Some online courses also encourage you to do optional hands-on activities at home when safe and feasible (for example, building a simple circuit for physics or extracting DNA from fruit in biology) to reinforce learning. Still, core assessments will use the provided simulations so all students can do them. The main difference is you won’t be physically in a school lab, but you’ll still learn how to hypothesize, observe results, and analyze data. Teachers often supplement with videos of real experiments to show you how it looks in real life. Assessment of labs in online courses will be based on your written analysis, calculations, and sometimes observations you record from the simulation. So, while the format differs, you will get a lab experience online. It’s pretty effective: studies and feedback have shown that virtual labs can also teach the concepts and skills. Plus, you gain extra skills in using digital tools. When you eventually go to university, you might have in-person labs, but you’ll be prepared with the foundational knowledge of experimental methods from your online course. And don’t worry – universities fully accept the lab component of online courses as meeting requirements, since the school issuing the credit attests that you’ve achieved those expectations.

How can I register for an online Grade 12 science course with Canadian Virtual School?

Registering with CVS is straightforward. Canadian Virtual School offers Grade 12 Biology (SBI4U), Grade 12 Chemistry (SCH4U), and Grade 12 Physics (SPH4U) as fully online, asynchronous courses. To get started, visit the CVS website’s course pages for SBI4U (Biology), SCH4U (Chemistry), or SPH4U (Physics) – there you’ll find detailed course outlines, prerequisites, and how to enroll. When you’re ready to sign up, use the online registration form on the CVS site or go directly to the CVS Registration page to create an account and select your course. You can register at any time of the year (CVS offers continuous enrollment, so there are no strict semester start dates – a great flexibility if you want to begin a course mid-year or in summer). After registering, you’ll gain access to the course content and be assigned a certified teacher who will guide you, grade your work, and answer your questions. CVS courses are self-paced, meaning you can work through the lessons on your schedule (ideal for balancing other commitments). Remember the prerequisite: you must show that you’ve completed the Grade 11 course (e.g., provide a transcript) during registration. Once enrolled, you’ll have up to 12 months (depending on CVS policies) to complete the course, but motivated students can finish sooner. Upon completion, CVS will issue a report card. If you’re an Ontario student, they’ll send your mark to OUAC/OCAS for university/college admissions just like your regular school would. If you have any questions, CVS’s admissions team is invaluable – you can contact them through the website for guidance on the process. In summary, head to the CVS website, fill out the registration for your chosen science course, and you’ll be on your way to earning your Grade 12 science credit online!


In conclusion, Grade 12 science courses are door-openers to various exciting post-secondary opportunities. By understanding the content and role of Biology vs Chemistry vs Physics, you can make an informed decision that aligns with your academic strengths and career aspirations. Whether you choose one science or all three, remember that these courses will equip you with knowledge and skills that go far beyond the textbook, from critical thinking to problem-solving to scientific literacy. And if flexibility or scheduling is a concern, consider pursuing your OSSD science credits online through an accredited institution like Canadian Virtual School.

Ready to take the next step? Canadian Virtual School (CVS) offers all three Grade 12 sciences as flexible online courses. You can learn at your own pace, anywhere, while earning an official OSSD credit. This is a great option to get the necessary courses, whether fitting an extra science into your timetable or preferring an online learning style. Don’t wait to chase your academic goals. Explore our course pages for SBI4U, SCH4U, and SPH4U to learn more about each course, or register now to secure your spot. Make your Grade 12 year count with the right science course, and set yourself up for success in university and beyond!